An antithymocyte serum noncytotoxic to myeloid progenitor cells: candidate serum for prevention of graft-versus-host disease in bone marrow transplantation. - Suppr | 超能文献

An antithymocyte serum noncytotoxic to myeloid progenitor cells: candidate serum for prevention of graft-versus-host disease in bone marrow transplantation.

作者信息

Foon K A, Fitchen J H, Billing R J, Belzer M B, Terasaki P I, Cline M J

出版信息

Clin Immunol Immunopathol. 1980 Aug;16(4):416-22. doi: 10.1016/0090-1229(80)90183-x.

DOI:10.1016/0090-1229(80)90183-x

Abstract

摘要

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An antithymocyte serum noncytotoxic to myeloid progenitor cells: candidate serum for prevention of graft-versus-host disease in bone marrow transplantation.

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Prevention or reduction of GVH reaction: physical separation of immunocompetent cells and immunosuppressive potential of antithymocyte serum.移植物抗宿主反应的预防或减轻：免疫活性细胞的物理分离及抗胸腺细胞血清的免疫抑制潜能。

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Anti-human thymocyte globulin (ATG) for prophylaxis and treatment of graft-versus-host disease in recipients of allogeneic marrow grafts.抗人胸腺细胞球蛋白（ATG）用于异基因骨髓移植受者移植物抗宿主病的预防和治疗。

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In vivo T cell depletion with low-dose rabbit antithymocyte globulin results in low transplant-related mortality and low relapse incidence following unrelated hematopoietic stem cell transplantation.低剂量兔抗胸腺细胞球蛋白进行体内T细胞清除，可使非亲缘造血干细胞移植后移植相关死亡率降低，复发率也降低。

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[Bone marrow transplantation and (or) immunosuppression with antithymocyte globulin in the treatment of aplastic anemia].[骨髓移植和（或）用抗胸腺细胞球蛋白进行免疫抑制治疗再生障碍性贫血]

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