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肾移植后儿童骨骼。X线表现与甲状旁腺激素量的相关性(作者译)

[The child's skeleton following renal transplant. A correlation of the radiographic findings to the amount of parathormone (author's transl)].

作者信息

Hegenbarth R, Offner G, Hehrmann R, Fritsch R

出版信息

Radiologe. 1980 Aug;20(8):400-5.

PMID:6997923
Abstract

The skeletal X-rays (magnification radiography of hand, pelvis, knee and shoulder joint) of 20 children before and after successful kidney transplantation were compared with the parathormone concentrations measured in the interval closest to the roentgenological examination. In 19 children, renal osteodystrophy existed before kidney transplantation, which was diagnosed based on the following radiographic findings of varying frequency: rarefaction and fuzziness of the spongiosa, fraying of metaphysical ends, widening of the growth plates, subperiosteal resorption and acroosteolysis. The parathormone concentrations were definitely increased before kidney transplantation. After kidney transplantation the abnormal radiographic findings receded corresponding to normalisation of the parathormone concentrations. Nevertheless, in 14 out of 19 children a rarefaction of the spongiosa remained, the cause of which is presumed to be steroid therapy.

摘要

对20名儿童成功进行肾移植前后的骨骼X线片(手部、骨盆、膝关节和肩关节放大X线摄影)与在最接近放射学检查的时间段内测得的甲状旁腺激素浓度进行了比较。19名儿童在肾移植前存在肾性骨营养不良,根据以下不同频率的放射学表现进行诊断:海绵质稀疏和模糊、干骺端磨损、生长板增宽、骨膜下吸收和肢端骨质溶解。肾移植前甲状旁腺激素浓度明显升高。肾移植后,异常放射学表现随着甲状旁腺激素浓度的正常化而消退。然而,19名儿童中有14名仍存在海绵质稀疏,推测其原因是类固醇治疗。

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