Katinas G S, Rekhacheva I P
Arkh Anat Gistol Embriol. 1980 Apr;78(4):98-106.
The aim of the work is to demonstrate how it is possible to get informations of differentiation in muscle fibres by means of evaluating the dynamics of statistical distribution moments. Combinations of various directions of time changes of the standard deviations, asymmetry and excess give the possibility to construct tables in order to get immediate informations on changes occurring in different parts of the distribution (and, hence, on the course of the muscle fibres development) during the whole time of observation (age dynamics of NAD-H-D activity in fibres of musculus serratus ventralis in Wistar rats is studied as an example). Analysing dynamics, as well as real distribution features of the muscle fibres, we got doubtful on the presence of muscle fibre types that could be considered as independent (though possibly as over-lapping) populations. Various differentiation rates of the muscle fibres with different optic density do not mean development of a certain population, but rather reflect an increasing process of development of a part of a single muscle fibres complex, where separate members have various properties and in the course of development they smoothly change them in such a way that uninterruption and continuation of possible intermediate conditions is kept along the whole variational curve. This method could be applied to analyse any other objects after any quantitative sign.
这项工作的目的是展示如何通过评估统计分布矩的动态变化来获取肌肉纤维分化的信息。标准差、不对称性和偏度随时间变化的不同方向的组合,使得构建表格成为可能,以便在整个观察期间(以研究Wistar大鼠腹侧锯肌纤维中NAD - H - D活性的年龄动态为例),立即获取分布不同部分发生的变化信息(从而了解肌肉纤维发育过程)。通过分析动态变化以及肌肉纤维的实际分布特征,我们对是否存在可被视为独立(尽管可能有重叠)群体的肌肉纤维类型表示怀疑。不同光学密度的肌肉纤维的不同分化速率并不意味着某个特定群体的发育,而是反映了单个肌肉纤维复合体中一部分的发育进程的增加,其中各个成员具有不同的特性,并且在发育过程中它们以这样一种方式平稳地改变这些特性,即在整个变化曲线上保持可能的中间状态的不间断和连续性。该方法可应用于根据任何定量特征分析任何其他对象。