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[幼鼠功能不同肌肉中琥珀酸脱氢酶活性与年龄变化]

[Age and changes in succinate dehydrogenase activity in functionally different muscles of the young rat].

作者信息

Rekhacheva I P, Sapronenkova I N, Chufarina S V, Novikova V V, Kozhina S Iu

出版信息

Arkh Anat Gistol Embriol. 1984 Jul;87(7):79-82.

PMID:6487089
Abstract

The antigravitational m. triceps brachii, its antagonist m. brachialis and the muscle having a universal functional specialization--m. serratus ventralis--have been studied in 35 male rats of Wistar strain, 60-105-day-old. Succinate dehydrogenase activity is determined in muscle fibers. Changes in the muscle fibers continue after the rats reach their sex maturation. Certain stageness of the process is observed, but the division of the period into separate steps either is absent (m. brachials), or their number is not great as compared to those during the 1st--60th days after birth. The borders of the periods in the muscles studied coinside (the 70th--74th day). Although it is possible to reveal the periods and separate steps in the changes occurring in the muscle fibers and in the muscles of the animals having reached their sex maturation, nevertheless, the borders between them are not distinct, the reconstruction during this age proceeds slower and more smoothely than before the sex maturation. It is possible that in young rats after sex maturation differentiation of the muscle fibers continues and that, in its turn, stimulates further specialization of the muscles as organs. The changes in the muscle fibers revealed histochemically occur most slowly under a low static loading, and when loading of various modality (kinetic and static) are combined, they are mostly pronounced.

摘要

对35只60 - 105日龄的雄性Wistar大鼠的抗重力肌肱三头肌、其拮抗肌肱肌以及具有普遍功能特化的肌肉——腹侧锯肌进行了研究。测定了肌纤维中的琥珀酸脱氢酶活性。大鼠达到性成熟后,肌纤维仍会持续发生变化。观察到该过程具有一定的阶段性,但该时期并未划分为单独的阶段(肱肌),或者与出生后第1至60天相比,阶段数量不多。所研究肌肉的阶段界限一致(第70至74天)。尽管可以揭示性成熟动物的肌纤维和肌肉中发生的变化的时期和单独阶段,然而,它们之间的界限并不明显,这个年龄段的重建过程比性成熟前进行得更慢、更平稳。性成熟后的幼鼠中,肌纤维可能继续分化,进而刺激肌肉作为器官的进一步特化。组织化学显示,在低静态负荷下,肌纤维的变化发生得最慢,而当各种形式(动态和静态)的负荷相结合时,变化最为明显。

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