Weissmann H S, Frank M S, Rosenblatt R, Sugarman L A, Freeman L M
Gastrointest Radiol. 1980 Aug 15;5(3):215-23. doi: 10.1007/BF01888633.
Technetium-99m IDA cholescintigraphy has provided a new, noninvasive means of visualizing biliary tract function. It has become the procedure of choice in patients with suspected acute cholecystitis because of its ability to most accurately detect functional obstruction or patency of the cystic duct as opposed to ultrasound's ability to detect only anatomic changes such as the presence of calculi or a thickened gallbladder wall. These latter findings are more important in establishing the diagnosis of chronic cholecystitis where ultrasound shares a position of prime importance with the oral cholecystogram. Tc-99m IDA cholescintigraphy has also been particularly useful in evaluating bile leaks, biliary-enteric anastomosis patency and the post-cholecystectomy patient with recurrent pain. In the patient with cholestasis, ultrasound is usually the procedure of choice since it establishes whether or not ductal dilatation is present and frequently can determine the cause of obstruction. Cholescintigraphy has played an ancillary role in many cases by demonstrating the level of partial obstruction, but it does not have the anatomic resolution to visualize the cause of obstruction. Occasionally, in the evaluation of cholestasis, cholescintigraphy has proven to be the only modality which has identified the presence of acute common duct obstruction or localized intrahepatic ductal obstruction. All in all, Tc-99m IDA cholescintigraphy has had a dramatic impact upon hepatobiliary diagnosis.
锝-99m 亚氨基二乙酸(IDA)肝胆闪烁显像提供了一种可视化胆道功能的新的非侵入性方法。由于其能够最准确地检测胆囊管的功能性梗阻或通畅情况,而超声只能检测诸如结石存在或胆囊壁增厚等解剖学变化,因此它已成为疑似急性胆囊炎患者的首选检查方法。在确立慢性胆囊炎的诊断方面,后一种发现更为重要,在这方面超声与口服胆囊造影一样具有首要地位。锝-99m IDA 肝胆闪烁显像在评估胆漏、胆肠吻合口通畅情况以及胆囊切除术后复发性疼痛的患者方面也特别有用。对于胆汁淤积患者,超声通常是首选检查方法,因为它能确定是否存在胆管扩张,并常常能确定梗阻原因。在许多情况下,肝胆闪烁显像通过显示部分梗阻的部位起到了辅助作用,但它没有足够的解剖分辨率来显示梗阻原因。偶尔,在胆汁淤积的评估中,肝胆闪烁显像已被证明是唯一能确定急性胆总管梗阻或局限性肝内胆管梗阻存在的检查方法。总而言之,锝-99m IDA 肝胆闪烁显像对肝胆疾病的诊断产生了巨大影响。