Eckert B S, Koons S J, Schantz A W, Zobel C R
J Cell Biol. 1980 Jul;86(1):1-5. doi: 10.1083/jcb.86.1.1.
Using an antibody specific for creatine phosphokinase (CPK), we have discovered an association between that enzyme and the cytoskeleton. Immunofluorescence observations show that CPK is associated with intermediate filaments in PTK cells and BALB/3T3 cells. The CPK distribution also follows intermediate filaments when cells are treated with colchicine.
利用一种对肌酸磷酸激酶(CPK)具有特异性的抗体,我们发现了该酶与细胞骨架之间的关联。免疫荧光观察表明,CPK与PTK细胞和BALB/3T3细胞中的中间丝相关联。当用秋水仙碱处理细胞时,CPK的分布也与中间丝一致。