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肌酸磷酸激酶与培养的哺乳动物细胞细胞骨架的关联。

Association of creatine phosphokinase with the cytoskeleton of cultured mammalian cells.

作者信息

Eckert B S, Koons S J, Schantz A W, Zobel C R

出版信息

J Cell Biol. 1980 Jul;86(1):1-5. doi: 10.1083/jcb.86.1.1.

DOI:10.1083/jcb.86.1.1
PMID:6998982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2110669/
Abstract

Using an antibody specific for creatine phosphokinase (CPK), we have discovered an association between that enzyme and the cytoskeleton. Immunofluorescence observations show that CPK is associated with intermediate filaments in PTK cells and BALB/3T3 cells. The CPK distribution also follows intermediate filaments when cells are treated with colchicine.

摘要

利用一种对肌酸磷酸激酶（CPK）具有特异性的抗体，我们发现了该酶与细胞骨架之间的关联。免疫荧光观察表明，CPK与PTK细胞和BALB/3T3细胞中的中间丝相关联。当用秋水仙碱处理细胞时，CPK的分布也与中间丝一致。

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Association of creatine phosphokinase with the cytoskeleton of cultured mammalian cells.肌酸磷酸激酶与培养的哺乳动物细胞细胞骨架的关联。
J Cell Biol. 1980 Jul;86(1):1-5. doi: 10.1083/jcb.86.1.1.
2
Immunofluorescence and inhibitor studies on creatine kinase and mitosis.
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Eur J Cell Biol. 1987 Oct;44(2):214-8.
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[Decreased level of immunoreactive creatine phosphokinase BB isoenzymes in the brain of patients with schizophrenia and senile dementia of the Alzheimer type].
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Topically applied growth factors change skin cytoplasmic creatine kinase activity and distribution and produce abnormal keratinocyte differentiation in murine skin.
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In vitro differentiation of teratomas and the distribution of creatine phosphokinase and plasminogen activator in teratocarcinoma-derived cells.畸胎瘤的体外分化以及肌酸磷酸激酶和纤溶酶原激活剂在畸胎癌衍生细胞中的分布。
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Immunoelectron microscopic investigation of creatine kinase BB-isoenzyme after cerebral ischemia in gerbils.沙土鼠脑缺血后肌酸激酶BB同工酶的免疫电子显微镜研究
Acta Neuropathol. 1993;86(5):447-55. doi: 10.1007/BF00228579.
4
Isoenzyme-specific localization of M-line bound creatine kinase in myogenic cells.肌原细胞中M线结合肌酸激酶的同工酶特异性定位
J Muscle Res Cell Motil. 1983 Aug;4(4):429-41. doi: 10.1007/BF00711948.
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Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.在培养的成纤维细胞中，线粒体与微管相关联，而与中间丝无关。
Proc Natl Acad Sci U S A. 1982 Jan;79(1):123-6. doi: 10.1073/pnas.79.1.123.
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本文引用的文献

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The comparative enzymology of creatine kinases. I. Isolation and characterization from chicken and rabbit tissues.肌酸激酶的比较酶学。I. 从鸡和兔组织中分离及鉴定
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The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin.兔骨骼肌收缩的调节。I. 原肌球蛋白-肌钙蛋白复合物与肌动蛋白及肌球蛋白蛋白水解片段相互作用的生化研究。
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10
A protein that binds specifically to the M-line of skeletal muscle is identified as the muscle form of creatine kinase.一种与骨骼肌M线特异性结合的蛋白质被鉴定为肌酸激酶的肌肉形式。
Proc Natl Acad Sci U S A. 1973 Mar;70(3):702-5. doi: 10.1073/pnas.70.3.702.