Insulin, prolactin, and cortisol in acute myocardial infarction.

Despite the wide clinical spectrum of acute myocardial infarction, changes in various hormones, e.g., insulin, prolactin, and cortisol, have been observed in these cases separately. The present study was designed to see the changes of these hormones simultaneously and to follow them up along with the clinical improvement of the patient. Sixty nonobese, nondiabetic, and nonhypertensive patients of confirmed acute myocardial infarction (mean age 53 years) of which 54 were males were selected against 44 controls. Insulin, prolactin, an cortisol were estimated by radioimmunoassay technique. From the results it is presumed that there is a direct interrelationship between these hormones with the biochemical electrocardiographic, and clinical state of the patient.