Rogal'skiĭ V Ia
Vopr Onkol. 1980;26(9):12-7.
Carcinoembryonic antigen (CEA) was detected in an indirect Coons test in cells of different organs i. e. stomach, esophagus, small intestine, bronchi, trachea, mucosal bronchial glands. By double diffusion in gel CEA has also been found in gastric, bronchial and vaginal mucus. The author considers CEA to be a component of mucus-producing cells. The increased CEA concentration in the blood of tumor patients is due to its secretion by tumor cells and its reverse absorption as well as excretion and destruction. The increased CEA level in the blood of patients with non-tumor pathology is related with increased excretion and destruction of CEA-producing cells.
在间接库恩氏试验中，在不同器官（即胃、食管、小肠、支气管、气管、支气管黏膜腺）的细胞中检测到癌胚抗原（CEA）。通过凝胶双向扩散法，在胃黏液、支气管黏液和阴道黏液中也发现了CEA。作者认为CEA是黏液分泌细胞的一个组成部分。肿瘤患者血液中CEA浓度升高是由于肿瘤细胞分泌CEA以及CEA的逆向吸收、排泄和破坏所致。非肿瘤性病变患者血液中CEA水平升高与产生CEA的细胞排泄和破坏增加有关。
