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[重症肌无力患者血清与健康受试者及重症肌无力患者胸腺淋巴细胞表面抗原结构之间的反应]

[Reaction between myasthenia patients' sera and the antigenic structure of the surface of thymic lymphocytes of healthy subjects and myasthenia gravis patients].

作者信息

Gnezditskaia E V, Beletskaia L V, Ippolitov I Kh, Malkina L A, Shagal D I

出版信息

Biull Eksp Biol Med. 1980 Oct;90(10):462-4.

PMID:7000198
Abstract

It has been established that sera from myasthenia patients contain in 42% of cases IgG antibodies to the point antigenic structure on the lymphocyte surface of the human thymus, spleen and lymph nodes. This antigenic structure is less pronounced on the lymphocytes from the thymus of normal subjects as compared with lymphocytes from the spleen and lymph nodes. On the contrary, the thymocytes from myasthenia patients show an elevated content of the antigen in question and do not differ in this respect from lymphocytes of the peripheral lymphoid organs of normal man.

摘要

已经确定,在42%的重症肌无力患者血清中含有针对人胸腺、脾脏和淋巴结淋巴细胞表面点状抗原结构的IgG抗体。与脾脏和淋巴结的淋巴细胞相比,正常受试者胸腺淋巴细胞上的这种抗原结构不太明显。相反,重症肌无力患者的胸腺细胞中上述抗原含量升高,在这方面与正常男性外周淋巴器官的淋巴细胞没有差异。

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