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幼年大鼠和小鼠中末端转移酶阳性(TdT+)细胞的短暂群体。

Transient populations of terminal transferase positive (TdT+) cells in juvenile rats and mice.

作者信息

Sasaki R, Bollum F J, Goldschneider I

出版信息

J Immunol. 1980 Dec;125(6):2501-3.

PMID:7000902
Abstract

Transient populations of TdT+ cells are present in peripheral blood, lung, liver, and spleen of rats and mice between birth and 7 wk of age. TdT+ blood cells appear to be post-thymic cells, as evidenced by their absence from nu/nu mice and their pattern of TdT fluorescence. TdT+ cells in lung, liver, and spleen appear to be prethymic cells. All transient populations of TdT+ cells are sensitive to dexamethasone. Only TdT+ cells in bone marrow and thymus persist into adult life.

摘要

在出生至7周龄的大鼠和小鼠的外周血、肺、肝和脾中存在短暂的末端脱氧核苷酸转移酶(TdT)阳性细胞群。TdT阳性血细胞似乎是胸腺后细胞,这在裸鼠中不存在以及它们的TdT荧光模式中得到证明。肺、肝和脾中的TdT阳性细胞似乎是胸腺前细胞。所有短暂的TdT阳性细胞群对地塞米松敏感。只有骨髓和胸腺中的TdT阳性细胞持续到成年期。

相似文献

1
Transient populations of terminal transferase positive (TdT+) cells in juvenile rats and mice.幼年大鼠和小鼠中末端转移酶阳性(TdT+)细胞的短暂群体。
J Immunol. 1980 Dec;125(6):2501-3.
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引用本文的文献

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Terminal deoxynucleotidyl transferase activities and glucocorticoid receptors in leukaemia.白血病中的末端脱氧核苷酸转移酶活性与糖皮质激素受体
Br J Cancer. 1981 Jul;44(1):63-7. doi: 10.1038/bjc.1981.148.
2
Detection of terminal transferase in paraffin sections with the immunoperoxidase technique.用免疫过氧化物酶技术检测石蜡切片中的末端转移酶。
Am J Pathol. 1981 Dec;105(3):241-54.
3
Sialyltransferase activity as a marker for the differentiation of lymphocytes. Increase in sialyltransferase activity of blasts from acute lymphoblastic leukaemia cases by 12-o-tetradecanoylphorbol-13-acetate (TPA).
唾液酸转移酶活性作为淋巴细胞分化的标志物。12-O-十四烷酰佛波醇-13-乙酸酯(TPA)使急性淋巴细胞白血病病例中原始细胞的唾液酸转移酶活性增加。
Clin Exp Immunol. 1982 Feb;47(2):381-8.
4
Isolation and characterization of bovine and mouse terminal deoxynucleotidyltransferase cDNAs expressible in mammalian cells.可在哺乳动物细胞中表达的牛和小鼠末端脱氧核苷酸转移酶cDNA的分离与鉴定。
Nucleic Acids Res. 1986 Jul 25;14(14):5777-92. doi: 10.1093/nar/14.14.5777.
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T cell recruitment from the thymus to the spleen in tumor-bearing mice. I. Analysis of recruited cells by surface markers.荷瘤小鼠中T细胞从胸腺向脾脏的募集。I. 通过表面标志物对募集细胞的分析。
Cancer Immunol Immunother. 1986;22(1):37-42. doi: 10.1007/BF00205714.