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[糖尿病肾病。关于病因发病机制、临床及治疗方面的现状与实际考量综述]

[Diabetic nephropathy. Review of the current status and practical considerations concerning etiopathogenetic, clinical and therapeutic aspects].

作者信息

Martini P F, Segoloni G P, Jeantet A, Giachino G, Mangiarotti G, Nebiolo P E, Longo L, Piancino G

出版信息

Minerva Med. 1980 Oct 6;71(38):2709-23.

PMID:7001279
Abstract

Reference is made to personal research and clinical experience, coupled with a select bibliography, in a survey of the most significant current knowledge with regard to diabetic nephropathy, designed for the nonspecialist practitioner and intended to enable him to update his knowledge without plunging into details, and to quickly decide what measures he should adopt in his daily practice. Questions of histopathology and aetiopathogenesis are examined, together with the relations between proteinuria, hypertension, renal function, and diabetic nephropathy. The clinical profile and progress of the disease are illustrated. Lastly, an account is given of the conventional modes of treatment, and of the still partly unsatisfactory results offered by more recent forms of replacement therapy (dialysis and transplantation).

摘要

本文参考了个人研究和临床经验,并结合精选的参考文献,对糖尿病肾病的当前最重要知识进行了综述。该综述是为非专科医生设计的,旨在使他们无需深入细节就能更新知识,并能迅速决定在日常实践中应采取何种措施。文中探讨了组织病理学和病因发病机制问题,以及蛋白尿、高血压、肾功能与糖尿病肾病之间的关系。阐述了该疾病的临床特征和进展。最后,介绍了传统的治疗方式,以及近期替代疗法(透析和移植)仍部分不尽人意的治疗结果。

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