Herman A, Adar R, Rubinstein Z
Diabetes. 1978 Oct;27(10):975-81. doi: 10.2337/diab.27.10.975.
Translumbar aortographies performed in 91 patients for limiting leg ischemia were reviewed, and stenosis was graded by points from one (normal vessel) to five (complete occlusion) for each vessel. Of 62 nondiabetic patients, 18 (29 per cent) were impotent, while of 29 diabetics, 17 (58.6 per cent) were impotent (p less than 0.01). Significantly greater stenosis (p less than 0.005) was found in the internal pudendal arteries of impotent patients when compared statistically with potent patients. This was true for the group as a whole, for diabetics and nondiabetics, and for patients over 50 years old both with and without diabetes. There was no significant difference in the extent of stenosis of the iliac arteries (common and internal) between potent and impotent patients. There was also no significant difference in the pattern of stenosis between diabetic and nondiabetic patients in the group as a whole and also in the potent and impotent subgroups analyzed separately. Neither diminished femoral pulses nor aortographic evidence of external iliac and common femoral arterial stenosis correlated significantly with impotence. These observations indicate that vascular lesions are as important in diabetics as in nondiabetics in the genesis of impotence. Clinical implications regarding diagnostic investigations and treatment are discussed.
回顾了91例因下肢缺血而行经腰主动脉造影的患者,对每条血管的狭窄程度按1分(血管正常)至5分(完全闭塞)进行分级。在62例非糖尿病患者中,18例(29%)有阳痿,而在29例糖尿病患者中,17例(58.6%)有阳痿(p<0.01)。与有性功能的患者相比,阳痿患者的阴部内动脉狭窄程度在统计学上显著更高(p<0.005)。这在整个组、糖尿病患者和非糖尿病患者以及50岁以上有糖尿病和无糖尿病的患者中均如此。有性功能和阳痿患者的髂动脉(总动脉和内动脉)狭窄程度无显著差异。在整个组以及分别分析的有性功能和阳痿亚组中,糖尿病患者和非糖尿病患者的狭窄模式也无显著差异。股动脉搏动减弱以及髂外动脉和股总动脉狭窄的主动脉造影证据与阳痿均无显著相关性。这些观察结果表明,在阳痿的发生中,血管病变在糖尿病患者和非糖尿病患者中同样重要。文中讨论了关于诊断性检查和治疗的临床意义。