O'Connor M D, Matthews E K
Horm Metab Res Suppl. 1980;Suppl 10:149-53.
Laser light-scattering techniques have been used to study the effects of polyanions on the time-dependent interaction of (i) polystyrene particles and (ii) insulin-containing granules isolated from pancreatic islets. New evidence of a major effect of polyanions on secretory granule aggregation is presented. The possible importance of intracellular polyanions in restricting the aggregation and hence fusion of secretory granules, especially in the presence of Ca2+, is discussed.
激光散射技术已被用于研究聚阴离子对（i）聚苯乙烯颗粒和（ii）从胰岛分离的含胰岛素颗粒的时间依赖性相互作用的影响。本文提供了聚阴离子对分泌颗粒聚集有重大影响的新证据。讨论了细胞内聚阴离子在限制分泌颗粒聚集进而融合方面的可能重要性，特别是在存在Ca2+的情况下。
