Hagan W E, Leonard G L, Ichinose H, Cox R H
Laryngoscope. 1980 Dec;90(12):1962-72. doi: 10.1288/00005537-198012000-00006.
The benign, monomorphic adenoma, derived from the respiratory epithelium of the middle ear, is a well circumscribed, greyish, avascular tumor. Its histology--documented by light and electron micrographs contained in this report--supports a distinct entity and pathogenesis apart from the malignant adenocarcinoma. Utilizing two case reports, this compendium emphasizes the clinical presentations, as well as radiographic and audiometrical characteristics, of the tumor. The first case represents the typical tumor with conductive hearing loss. The second case is the first reported facial paralysis associated with hemorrhagic infarction of an adenoma which was reversible by surgical resection of the tumor. Based on the histology and four year postoperative follow-up, the authors conclude the adenoma may be effectively managed by surgical resection.
源自中耳呼吸上皮的良性单形性腺瘤是一种边界清晰、呈灰色、无血管的肿瘤。本报告中的光镜和电镜照片记录了其组织学特征,支持它是一种有别于恶性腺癌的独特实体及发病机制。本综述通过两个病例报告,着重阐述了该肿瘤的临床表现以及影像学和听力测定特征。第一个病例代表了伴有传导性听力损失的典型肿瘤。第二个病例是首次报告的与腺瘤出血性梗死相关的面瘫,通过手术切除肿瘤后可恢复。基于组织学检查和术后四年的随访,作者得出结论,腺瘤可通过手术切除得到有效治疗。