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[甲基泼尼松龙在尸体肾移植治疗中的应用]

[The use of methylprednisolone in the therapy of renal transplants from cadavers].

作者信息

Selva S, Vallino F, Elli A, Trazzi R

出版信息

Minerva Chir. 1980 Oct 31;35(20):1581-8.

PMID:7005747
Abstract

The role of steroids, and specifically of methylprednisolone, in the pharmacological treatment of cadaver kidney transplants is discussed. The action mechanisms of the substance, and the modalities for its use in basic treatment of the transplanted organ and in rejection crisis are described. Finally, the results obtained in 147 transplanted patients, the complications involved and the measures taken to eliminate, or at least reduce, the problems of prolonged steroid therapy are reviewed.

摘要

本文讨论了类固醇,特别是甲泼尼龙在尸体肾移植药物治疗中的作用。描述了该物质的作用机制,以及其在移植器官基础治疗和排斥反应危机中的使用方式。最后,回顾了147例移植患者所取得的结果、所涉及的并发症以及为消除或至少减少长期类固醇治疗问题而采取的措施。

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