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[结直肠癌中的同步和异时性病变]

[Synchronous and metachronous processes in colo-rectal carcinoma].

作者信息

Ottenjann R, Weissmann G, Fischer L I, von Rothkirch S, Frimberger E

出版信息

Fortschr Med. 1978 Nov 2;96(41):2075-9.

PMID:700594
Abstract

Polyps are often associated with carcinoma in the colon. The incidence of colorectal polyps with single carcinoma is up to 25% and with multiple carcinoma up to 75%. Not infrequently both synchronous and metachronous carcinoma are found in the colon and rectum. These findings emanate from a sample of 367 patients (in this hospital) with colorectal carcinoma during the period 1973 to 1977. The incidence of synchronous and metachronous carcinoma as well as severe dysplasia (focal carcinoma) in adenomatous polyps was nearly 8%. In slightly more than 50% of cases involving a single carcinoma, there was no evidence of an accompanying condition or later development. In more than 20% of the cases single carcinoma was accompanied by synchronous and metachronous polyps. These figures eloquently illustrate the necessity for closely coordinated postoperative care of patients with colorectal carcinoma.

摘要

息肉常与结肠癌相关。伴有单发癌的大肠息肉发生率高达25%,伴有多发癌的高达75%。在结肠和直肠中,同时性和异时性癌并不罕见。这些发现来自于1973年至1977年期间(本院)367例结直肠癌患者的样本。腺瘤性息肉中同时性和异时性癌以及重度发育异常(局灶性癌)的发生率近8%。在略多于50%的单发癌病例中,没有伴随疾病或后期发展的证据。在超过20%的病例中,单发癌伴有同时性和异时性息肉。这些数据有力地说明了对结直肠癌患者进行密切协调的术后护理的必要性。

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