[对2400例患者抗红细胞自身致敏研究结果的分析]

[Analysis of results in studies on anti-erythrocyte auto-sensitization in 2400 patients].

作者信息

Vroclans-Deiminas M, Boivin P

出版信息

Rev Fr Transfus Immunohematol. 1980 May;23(2):105-17. doi: 10.1016/s0338-4535(80)80051-1.

Abstract

The authors report their experience since 1970 in the laboratory investigation of anti-erythrocyte auto-immunization. 2400 tests were performed, and the positive results were divided into 2 groups: --341 patients with a positive direct antiglobulin test; --502 patients without positive direct antiglobulin test, but with various abnormalities: positive elution, increased titer of cold agglutinin, auto-agglutinability of protease treated red cells... The immunohaematological and etiological data are described for each group. It appears: --that there is no significant difference in etiological data between the two groups; --that the direct antiglobulin test is not sufficient in investigation of anti-erythrocyte auto-immunization, but some other immunohaematologic tests are indispensable.

摘要

作者报告了他们自1970年以来在抗红细胞自身免疫实验室研究中的经验。共进行了2400次检测，阳性结果分为两组：——341例直接抗球蛋白试验阳性的患者；——502例直接抗球蛋白试验未呈阳性，但有各种异常情况的患者：洗脱阳性、冷凝集素效价升高、蛋白酶处理红细胞的自身凝集性……对每组的免疫血液学和病因学数据进行了描述。结果显示：——两组病因学数据无显著差异；——直接抗球蛋白试验在抗红细胞自身免疫的研究中并不充分，但一些其他免疫血液学检测是必不可少的。