Hanna S S, Warren W D, Galambos J T, Millikan W J
Can Med Assoc J. 1981 Jan 1;124(1):29-41.
The aim of the emergency management of bleeding varices is to stop the hemorrhage nonoperatively if possible, avoiding emergency shunt surgery, an operation that has a higher mortality than elective shunt surgery. Patients with an upper gastrointestinal hemorrhage should undergo endoscopy immediately to verify the diagnosis of bleeding varices. They can then be categorized according to whether they stop bleeding spontaneously (group 1), continue to bleed slowly (group 2) or continue to bleed rapidly (group 3). Group 1 patients are discussed in the second part of this two-part series. Group 2 patients are initially treated with vasopressin given intravenously; those who fail to respond should undergo emergency angiography and receive vasopressin intra-arterially. If this fails, patients at low surgical risk should undergo urgent shunt surgery; those at high risk do better with endoscopic sclerotherapy. Group 3 patients are also given an intravenous infusion of vasopressin. Patients at low surgical risk who continue to bleed then receive tamponade with a Sengstaken--Blakemore tube. If this fails, they undergo emergency creation of an H-shaped mesocaval shunt. Patients at high surgical risk who fail to respond to vasopressin given intravenously are next treated intra-arterially. If this fails they are given either endoscopic or transhepatic sclerotherapy.
静脉曲张破裂出血的急诊处理目的是尽可能通过非手术方法止血,避免进行急诊分流手术,因为该手术的死亡率高于择期分流手术。上消化道出血患者应立即接受内镜检查以确诊静脉曲张破裂出血。然后可根据患者是否自行止血(第1组)、持续缓慢出血(第2组)或持续快速出血(第3组)进行分类。在这个分为两部分的系列文章的第二部分讨论第1组患者。第2组患者最初静脉注射加压素治疗;治疗无效者应接受急诊血管造影并动脉内注射加压素。若此方法失败,手术风险低的患者应接受紧急分流手术;手术风险高的患者接受内镜硬化疗法效果更佳。第3组患者也静脉输注加压素。持续出血且手术风险低的患者随后用Sengstaken-Blakemore管进行压迫止血。若此方法失败,则进行急诊H形肠系膜上静脉-下腔静脉分流术。静脉注射加压素无反应且手术风险高的患者接下来接受动脉内治疗。若此方法失败,给予内镜或经肝硬化疗法。