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[肿瘤标志物在支气管癌诊断与治疗中的意义]

[Significance of tumor markers in the diagnosis and treatment of bronchial carcinoma].

作者信息

Gropp C, Havemann K

出版信息

Onkologie. 1980 Jun;3(3):133-8. doi: 10.1159/000214781.

Abstract

In bronchogenic carcinoma a variety of tumor markers have been described in the last few years. These markers are oncofetal proteins like the carcinoembryonic antigen (CEA), pregnancy-associated antigens like the pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG), and the beta-chorionic gonadotropin (beta-HCG), or normal proteins like isoferritin, coeruloplasmin and hormones. In addition, many attempts have been made to isolate tumor-specific antigens and proteins from lung tumor tissues. The clinical application of the different tumor markers for early diagnosis, staging and therapy control of lung cancer patients is described.

摘要

在过去几年里,支气管源性癌中已发现多种肿瘤标志物。这些标志物包括癌胚抗原(CEA)等癌胚蛋白、妊娠相关α2-糖蛋白(α2-PAG)和β-绒毛膜促性腺激素(β-HCG)等妊娠)等妊娠相关抗原,以及铁蛋白、铜蓝蛋白和激素等正常蛋白质。此外,人们还进行了许多尝试,从肺肿瘤组织中分离肿瘤特异性抗原和蛋白质。本文描述了不同肿瘤标志物在肺癌患者早期诊断、分期及治疗监测中的临床应用。

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