Gropp C, Havemann K
Onkologie. 1980 Jun;3(3):133-8. doi: 10.1159/000214781.
In bronchogenic carcinoma a variety of tumor markers have been described in the last few years. These markers are oncofetal proteins like the carcinoembryonic antigen (CEA), pregnancy-associated antigens like the pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG), and the beta-chorionic gonadotropin (beta-HCG), or normal proteins like isoferritin, coeruloplasmin and hormones. In addition, many attempts have been made to isolate tumor-specific antigens and proteins from lung tumor tissues. The clinical application of the different tumor markers for early diagnosis, staging and therapy control of lung cancer patients is described.
在过去几年里,支气管源性癌中已发现多种肿瘤标志物。这些标志物包括癌胚抗原(CEA)等癌胚蛋白、妊娠相关α2-糖蛋白(α2-PAG)和β-绒毛膜促性腺激素(β-HCG)等妊娠)等妊娠相关抗原,以及铁蛋白、铜蓝蛋白和激素等正常蛋白质。此外,人们还进行了许多尝试,从肺肿瘤组织中分离肿瘤特异性抗原和蛋白质。本文描述了不同肿瘤标志物在肺癌患者早期诊断、分期及治疗监测中的临床应用。