Tenovuo J, Söderling E, Anttonen T
Scand J Dent Res. 1980 Oct;88(5):430-5. doi: 10.1111/j.1600-0722.1980.tb01249.x.
Neither iodinated proteins nor iodinated, low-molecular weight compounds (e.g. iodinated tyrosine derivatives) could be detected in concentrated human salivary supernatant by using the Ce(SO4)2-method either directly or after thin-layer chromatography. Salivary sediment contained free I- ions, loosely bound iodine (released with saline) and strongly bound iodine (released with sonication, detergent and acid hydrolysis). A positive correlation between salivary and crevicular excretion of I- from plasma was observed. Thiocyanate ions, which competitively inhibit peroxidase-catalysed oxidation and iodination reactions and which are abundant in human saliva, possibly prevent the coupling of I- to protein in vivo although some human salivary proteins are very susceptible to iodination in vitro.
无论是使用硫酸铈（Ce(SO4)2）法直接检测，还是在薄层色谱分析后检测，在浓缩的人唾液上清液中均未检测到碘化蛋白质或碘化低分子量化合物（如碘化酪氨酸衍生物）。唾液沉淀物中含有游离碘离子、松散结合的碘（用盐水释放）和紧密结合的碘（用超声处理、洗涤剂和酸水解释放）。观察到唾液中碘离子与龈沟液中血浆碘离子排泄之间呈正相关。硫氰酸根离子可竞争性抑制过氧化物酶催化的氧化和碘化反应，且在人唾液中含量丰富，尽管一些人唾液蛋白在体外极易碘化，但它可能在体内阻止碘离子与蛋白质的结合。
