Hanno R, Bean S F
Am J Dermatopathol. 1980 Winter;2(4):363-6. doi: 10.1097/00000372-198000240-00013.
A variety of bullous eruptions have been reported in patients with Hodgkin's disease, among them erythema multiforme, herpesvirus infections, bullous impetigo, prurigo-like papules with vesicles, drug eruptions, bullous pemphigoid, dermatitis herpetiformis, and acquired epidermolysis bullosa. We now describe a patient whose bullous eruption was thought initially to be bullous pemphigoid. However, histopathologic examination of a bulla showed a lymphomatous infiltrate beneath an intraepidermal and subepidermal blister. These pathological findings seem to be unique and we interpret them to be those of bullous Hodgkin's disease.
据报道,霍奇金病患者会出现多种大疱性皮疹,其中包括多形红斑、疱疹病毒感染、大疱性脓疱病、伴有水疱的痒疹样丘疹、药物疹、大疱性类天疱疮、疱疹样皮炎和获得性大疱性表皮松解症。我们现在描述一名患者,其大疱性皮疹最初被认为是大疱性类天疱疮。然而,对一个水疱进行组织病理学检查发现,在表皮内和表皮下水疱下方有淋巴瘤浸润。这些病理发现似乎是独特的,我们将其解释为大疱性霍奇金病的病理表现。