Prokocimer M, Matzner Y, Polliack A
Hepatogastroenterology. 1980 Oct;27(5):401-6.
A patient with Philadelphia positive chronic granulocytic leukemia in clinical remission is described, who developed Shigella dysentery complicated by fatal toxic megacolon, pancytopenia and bone marrow aplasia. The difficulties of differential diagnosis between active ulcerative colitis and Shigella dysentery and problems relating to the management of these two disorders are discussed. Leukocyte function in chronic granulocytic leukemia and its role in infection in these patients is also briefly reviewed. The rare association of bone marrow aplasia and Shigellosis is stressed.
本文描述了一名处于临床缓解期的费城染色体阳性慢性粒细胞白血病患者，该患者发生了志贺氏菌痢疾，并发致命性中毒性巨结肠、全血细胞减少和骨髓再生障碍。文中讨论了活动性溃疡性结肠炎和志贺氏菌痢疾之间鉴别诊断的难点以及这两种疾病的管理相关问题。还简要回顾了慢性粒细胞白血病中的白细胞功能及其在这些患者感染中的作用。强调了骨髓再生障碍与志贺氏菌病的罕见关联。
