Flückiger M, Berger J, Casey P, Aeberhard P
Helv Chir Acta. 1980 Dec;47(5):659-62.
A double-blind randomised trial was carried out among 72 patients undergoing elective colorectal surgery. 37 patients received Metronidazole and Kanamycin systemically, 35 patients the same medicaments orally. We could not find any difference between the two ways of application. These results are in opposition to those of a comparable study of Birmingham, where the therapy was significantly less successful in the oral group. This fact is discussed and the parenteral, short-term prophylaxis is recommended.
对72例择期行结直肠手术的患者进行了一项双盲随机试验。37例患者全身应用甲硝唑和卡那霉素，35例患者口服相同药物。我们未发现两种用药方式之间存在任何差异。这些结果与伯明翰一项类似研究的结果相反，在该研究中口服组的治疗效果明显较差。对这一事实进行了讨论，并推荐采用胃肠外短期预防措施。
