Anton H J, Voit E
Microsc Acta. 1981 Jan;84(1):17-23.
A tissue can often be characterized by size and shape of its nuclei. For several purposes the population of nuclei is analyzed by using tissue sections. However, the relationships between the distribution of the sizes of the nuclei and that of their sections are not self-evident. Therefore, the cutting of spheres was simulated on a computer in order to clarify the relationships in at least a simple system. As each combination of different spheres results in a specific distribution of sections, it is often possible to decide without any calculations whether an observed histogram of sections originates from a system of spheres of the same or of different sizes, or of non-spherical objects.
组织通常可以通过其细胞核的大小和形状来表征。出于多种目的,通过使用组织切片来分析细胞核群体。然而,细胞核大小分布与其切片大小分布之间的关系并非显而易见。因此,在计算机上模拟球体的切割,以便至少在一个简单系统中阐明这些关系。由于不同球体的每种组合都会导致特定的切片分布,通常无需任何计算就可以确定观察到的切片直方图是源自相同大小或不同大小的球体系统,还是源自非球形物体系统。