Venturini S, Tamaro M, Monti-Bragadin C, Carlassare F
Mutat Res. 1981 Jan;88(1):17-22. doi: 10.1016/0165-1218(81)90085-9.
A series of angelicin derivatives were tested for their mutagenic activity with and without near-ultraviolet irradiation (NUV) in Salmonella typhimurium strains. After irradiation with NUV, the tested compounds induced different numbers of revertants in strain TA100, indicating that the mutational events involved are base substitutions. In the dark, 3 chemicals behaved as frame-shift mutagens causing reversion in strain TA98.
一系列当归素衍生物在鼠伤寒沙门氏菌菌株中，分别在有和没有近紫外辐射（NUV）的情况下进行了诱变活性测试。在用NUV照射后，受试化合物在TA100菌株中诱导出不同数量的回复突变体，表明所涉及的突变事件是碱基置换。在黑暗中，3种化学物质表现为移码诱变剂，可在TA98菌株中引起回复突变。
