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[用于治疗尿路感染的新型抗生素]

[New antibiotics in the treatment of urinary tract infections].

作者信息

Fuchs P, Lüthy R, Siegenthaler W

出版信息

Helv Chir Acta. 1978 Jul;45(3):217-21.

PMID:701059
Abstract

Based on the frequency of the isolated bacteria the antibiotics and chemotherapeutics commonly used in infections of the urinary tract are discussed. It turns out that ampicillin and sulphamethoxazole-trimethoprim are still the drugs of choice in the treatment of these bacterial diseases. A true advance is achieved by the introduction of carbenicillin and the new aminoglycoside amikacin. Carbenicillin can be used in Pseudomonas infections and is characterized by its low toxicity. Amikacin is the drug of choice against aminoglycoside-resistant gramnegative bacteria.

摘要

根据分离出的细菌的频率,讨论了常用于尿路感染的抗生素和化学治疗药物。结果表明,氨苄青霉素和磺胺甲恶唑-甲氧苄啶仍然是治疗这些细菌性疾病的首选药物。羧苄青霉素和新的氨基糖苷类药物丁胺卡那霉素的引入取得了真正的进展。羧苄青霉素可用于假单胞菌感染,其特点是毒性低。丁胺卡那霉素是对抗氨基糖苷类耐药革兰氏阴性菌的首选药物。

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