Laplante L, Beaudry C
Can Med Assoc J. 1975 Jun 14;112(13 Spec No):7-9.
Two groups, each of 20 patients, with urinary tract infection were randomly chosen and treated according to a double-blind procedure with either ampicillin, 500 mg, or trimethoprimsulfamethoxazole, either drug being given 4 times daily for 10 days. A number of features of the infections were studied: the occurrence of single or multiple attacks, the presence or absence of complications whether the lower or upper urinary tract was affected, favourably with ampicillin in sterilizing the urine of patients and the bacteria involved. Trimethoprim-sulfamethoxazole was found to compare with multiple and complicated urinary tract infections during a follow-up period of 3 months.
随机选取两组各20例尿路感染患者，按照双盲程序分别用500毫克氨苄西林或甲氧苄啶 - 磺胺甲恶唑进行治疗，两种药物均每日服用4次，持续10天。对感染的一些特征进行了研究：单次或多次发作的情况、有无并发症（无论下尿路还是上尿路是否受到影响）、氨苄西林在使患者尿液和所涉及细菌除菌方面的良好效果。在3个月的随访期内，发现甲氧苄啶 - 磺胺甲恶唑对多重和复杂性尿路感染有效。
