Sudmeier J L, Bell S J, Storm M C, Dunn M F
Science. 1981 May 1;212(4494):560-2. doi: 10.1126/science.7010607.
By use of cadmium-113 nuclear magnetic resonance spectroscopy, a specific calcium ion binding site has been identified in the bovine two-zinc insulin hexamer. This site is composed of six glutamyl carboxylate groups clustered in the center of the hexamer, and is distinct from the normal zinc ion binding sites.
通过使用镉-113核磁共振光谱法,在牛的双锌胰岛素六聚体中鉴定出了一个特定的钙离子结合位点。该位点由聚集在六聚体中心的六个谷氨酰羧基组成,与正常的锌离子结合位点不同。