生物合成人胰岛素的化学、物理和生物学特性。

Chemical, physical, and biologic properties of biosynthetic human insulin.

作者信息

Chance R E, Kroeff E P, Hoffmann J A, Frank B H

出版信息

Diabetes Care. 1981 Mar-Apr;4(2):147-54. doi: 10.2337/diacare.4.2.147.

DOI:10.2337/diacare.4.2.147

Abstract

Human insulin derived via recombinant DNA technology was tested extensively by a complex battery of analytic procedures. This product, which is designated biosynthetic human insulin, was found to be chemically, physically, and immunologically equivalent to pancreatic human insulin and biologically equivalent to both pancreatic human insulin and purified pork insulin.

摘要

通过重组DNA技术获得的人胰岛素，经过一系列复杂的分析程序进行了广泛测试。这种产品被命名为生物合成人胰岛素，结果发现它在化学、物理和免疫学方面与胰腺来源的人胰岛素等效，在生物学方面与胰腺来源的人胰岛素和纯化猪胰岛素等效。