脲酶在感染性结石形成中的作用：不同来源脲酶的比较
Role of urease in the formation of infection stones: comparison of ureases from different sources.
作者信息
Rosenstein I J, Hamilton-Miller J M, Brumfitt W
出版信息
Infect Immun. 1981 Apr;32(1):32-7. doi: 10.1128/iai.32.1.32-37.1981.
Abstract
Bacterial and vegetable ureases were found to differ in certain important respects. For maximal clinical relevance, in vitro studies on the pathogenic role of urease should use whole bacterial cells of Proteus spp., and urease inhibitors should be assessed without preincubation of enzyme with inhibitor. Urease from Proteus morganii was very different from ureases of other species of Proteus; this factor should be taken into account when infections with P. morganii are being treated.
摘要
人们发现细菌脲酶和植物脲酶在某些重要方面存在差异。为了使体外研究在临床方面具有最大相关性，关于脲酶致病作用的体外研究应使用变形杆菌属的完整细菌细胞，并且在评估脲酶抑制剂时，不应将酶与抑制剂预先孵育。摩根氏变形杆菌的脲酶与其他变形杆菌属物种的脲酶非常不同；在治疗摩根氏变形杆菌感染时应考虑到这一因素。
相似文献
1
Role of urease in the formation of infection stones: comparison of ureases from different sources.
Infect Immun. 1981 Apr;32(1):32-7. doi: 10.1128/iai.32.1.32-37.1981.
2
The effect of acetohydroxamic acid on the induction of bacterial ureases.
Invest Urol. 1980 Sep;18(2):112-4.
3
Inhibition of bacterial urease.
Invest Urol. 1973 Nov;11(3):234-8.
4
Genetic and biochemical diversity of ureases of Proteus, Providencia, and Morganella species isolated from urinary tract infection.
Infect Immun. 1987 Sep;55(9):2198-203. doi: 10.1128/iai.55.9.2198-2203.1987.
5
The ureases of Proteus strains in relation to virulence for the urinary tract.
J Med Microbiol. 1980 Nov;13(4):507-12. doi: 10.1099/00222615-13-4-507.
6
Inhibitors of bacterial urease: microbiological considerations on hydroxyurea influenza virus.
Boll Ist Sieroter Milan. 1982;61(6):513-5.
7
A Rare Opportunist, , Decreases Severity of Polymicrobial Catheter-Associated Urinary Tract Infection.
Infect Immun. 2019 Dec 17;88(1). doi: 10.1128/IAI.00691-19.
8
Cytotoxicity of the HpmA hemolysin and urease of Proteus mirabilis and Proteus vulgaris against cultured human renal proximal tubular epithelial cells.
Infect Immun. 1991 Jun;59(6):2036-42. doi: 10.1128/iai.59.6.2036-2042.1991.
9
Inhibition of urease activity by dipeptidyl hydroxamic acids.
Chem Pharm Bull (Tokyo). 1992 Oct;40(10):2764-8. doi: 10.1248/cpb.40.2764.
10
Urease activity of Proteus penneri.
J Clin Microbiol. 1987 Dec;25(12):2302-5. doi: 10.1128/jcm.25.12.2302-2305.1987.
引用本文的文献
1
Design and synthesis of terephthalic dihydrazide analogues as dual inhibitors of glycation and urease.
RSC Adv. 2025 Mar 28;15(12):9510-9520. doi: 10.1039/d5ra00459d. eCollection 2025 Mar 21.
2
Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment.
ACS Omega. 2023 Aug 23;8(35):31890-31898. doi: 10.1021/acsomega.3c03546. eCollection 2023 Sep 5.
3
Colorimetric Detection of Urease-Producing Microbes Using an Ammonia-Responsive Flexible Film Sensor.
Biosensors (Basel). 2022 Oct 17;12(10):886. doi: 10.3390/bios12100886.
4
Synthesis of Some Spiro Indeno[1,2-]pyrido[2,3-]Pyrimidine-5,3'-Indolines as New Urease Inhibitors.
Iran J Pharm Res. 2016 Winter;15(Suppl):55-63.
5
[Catheter-associated urinary tract infections].
Urologe A. 2015 Sep;54(9):1301-8;quiz 1308-10. doi: 10.1007/s00120-015-3912-2.
6
Selective enrichment and production of highly urease active bacteria by non-sterile (open) chemostat culture.
J Ind Microbiol Biotechnol. 2013 Oct;40(10):1095-104. doi: 10.1007/s10295-013-1310-6. Epub 2013 Jul 27.
7
Synthesis and activity of Helicobacter pylori urease and catalase at low pH.
Gut. 1997 Jan;40(1):25-30. doi: 10.1136/gut.40.1.25.
8
Potential virulence factors of Proteus bacilli.
Microbiol Mol Biol Rev. 1997 Mar;61(1):65-89. doi: 10.1128/mmbr.61.1.65-89.1997.
9
Proteus mirabilis urease: transcriptional regulation by UreR.
J Bacteriol. 1993 Jan;175(2):465-73. doi: 10.1128/jb.175.2.465-473.1993.
10
Molecular biology of microbial ureases.
Microbiol Rev. 1995 Sep;59(3):451-80. doi: 10.1128/mr.59.3.451-480.1995.
本文引用的文献
1
An improved selective medium for the formation of ascospores by Aspergillus nidulans.
Nature. 1962 Mar 17;193:1106. doi: 10.1038/1931106a0.
2
Hepatic coma.
Annu Rev Med. 1960;11:47-58. doi: 10.1146/annurev.me.11.020160.000403.
3
UREASE CATALYSIS. II. INHIBITION OF THE ENZYME BY HYDROXYUREA, HYDROXYLAMINE, AND ACETOHYDROXAMIC ACID.
J Biol Chem. 1965 Jun;240:2407-14.
4
UREASE CATALYSIS. I. STOICHIOMETRY, SPECIFICITY, AND KINETICS OF A SECOND SUBSTRATE: HYDROXYUREA.
J Biol Chem. 1965 Jun;240:2402-6.
5
Specific inhibition of urease by hydroxamic acids.
Biochim Biophys Acta. 1962 Dec 4;65:380-3. doi: 10.1016/0006-3002(62)91067-3.
6
The effect of acetohydroxamic acid on the induction of bacterial ureases.
Invest Urol. 1980 Sep;18(2):112-4.
7
Some properties and purifications of urease.
Biochim Biophys Acta. 1967 Sep 12;146(1):205-18. doi: 10.1016/0005-2744(67)90087-3.
8
Proteus vulgaris urease: in vitro inhibition by urea analogues.
Proc Soc Exp Biol Med. 1966 Jun;122(2):506-8. doi: 10.3181/00379727-122-31174.
9
Acetohydroxamate: bacterial urease inhibitor with therapeutic potential in hyperammonaemic states.
Nature. 1965 Oct 2;208(5005):46-8. doi: 10.1038/208046a0.
10
Inhibition of urease by metal ions.
Enzymologia. 1969 Jun 30;36(6):332-4.
Zotero 插件