May F B, Shapiro P A
J Prosthet Dent. 1981 May;45(5):550-7. doi: 10.1016/0022-3913(81)90045-7.
An attempt was made to obtain a soft-tissue seal around the neck of an endosseous implant using a section of root from another tooth in the oral cavity. Six implants were placed bilaterally in the mandibular first molar regions of three monkeys. Four of the six implants were lost during the experimental period. In at least three of the four situations, it was apparent that the animals had removed the implants despite chair restraint. On the basis of clinical evaluation of all implants and histologic examination of the two remaining implants, it was concluded that an epithelial attachment was not present. The absence of an attachment may have been caused by chronic inflammation around the implant wafer. While an epithelial attachment could not be demonstrated in this experiment, it is felt that the rationale for this research project remains valid. Several potential improvements in methodology are suggested.
尝试使用口腔中另一颗牙齿的一段牙根，在骨内种植体颈部周围获得软组织封闭。在三只猴子的双侧下颌第一磨牙区植入了六颗种植体。在实验期间，六颗种植体中有四颗丢失。在这四种情况中的至少三种情况下，很明显，尽管有椅子约束，动物还是将种植体取出了。根据对所有种植体的临床评估以及对剩余两颗种植体的组织学检查，得出的结论是不存在上皮附着。附着缺失可能是由种植体薄片周围的慢性炎症引起的。虽然在本实验中未能证明上皮附着，但认为该研究项目的基本原理仍然有效。提出了方法学上的几个潜在改进建议。
