Hempelmann E, Wilson R J
Mol Biochem Parasitol. 1981 Feb;2(3-4):197-204. doi: 10.1016/0166-6851(81)90100-6.
The ability to carry out the initial reaction of the pentose phosphate pathway was investigated with extracts of mouse erythrocytes infected with Plasmodium chabaudi, purified merozoites of P. knowlesi, and schizonts of P. falciparum grown in vitro in human erythrocytes. Glucose-6-phosphate dehydrogenase activity (G-6pd) was detected in extracts of all the cells after electrophoresis on polyacrylamide gels. Separate host cell and parasite glucose-6-phosphate dehydrogenase activities were demonstrated with extracts of P. knowlesi and P. falciparum but not with P. chabaudi.
利用感染了恰氏疟原虫的小鼠红细胞提取物、纯化的诺氏疟原虫裂殖子以及在人红细胞中体外培养的恶性疟原虫裂殖体，对戊糖磷酸途径初始反应的进行能力进行了研究。在聚丙烯酰胺凝胶上进行电泳后，在所有细胞的提取物中均检测到了葡萄糖-6-磷酸脱氢酶活性（G-6pd）。用诺氏疟原虫和恶性疟原虫的提取物证明了宿主细胞和寄生虫各自的葡萄糖-6-磷酸脱氢酶活性，但恰氏疟原虫的提取物未显示出这种差异。
