胰岛素栓剂的生物制药研究。
Biopharmaceutical study of insulin suppositories.
作者信息
Mesiha M S, Lobel S, Salo D P, Khaleeva L D, Zekova N Y
出版信息
Pharmazie. 1981;36(1):29-32.
PMID:7012849
Abstract
The possibility of insulin administration in suppository dosage form was studied, using different carriers. Highly significantly insulin absorption from the rabbit rectum was obtained by inserting insulin suppositories containing Brij 58 as absorption-promoting surfactant.
摘要
使用不同载体对胰岛素栓剂剂型给药的可能性进行了研究。通过插入含有作为吸收促进表面活性剂的聚山梨醇酯58的胰岛素栓剂，从兔直肠获得了高度显著的胰岛素吸收。
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