Menkes C J, Job Ch, Buneaux F, Delbarre F
Rev Rhum Mal Osteoartic. 1981 Mar;48(3):223-7.
At the end of a double blind clinical test carried out in 35 patients with classical rheumatoid arthritis, or progressive and with certain diagnosis, it does not appear that zinc sulphate given by mouth at dose of 600 mg/24 hours (divided up into 3 doses) may be a valid basic treatment. In fact, none of the classical clinical criteria (Richtie index, Lee index, etc.) nor laboratory criteria (E.S.R.) show any statistically significant change after 4 and 8 months. The discrepancy between these results and those previously published in discussed.
在对35例典型类风湿性关节炎患者或病情进展且诊断明确的患者进行的双盲临床试验结束时，口服硫酸锌，剂量为600毫克/24小时（分3次服用），似乎并不是一种有效的基础治疗方法。事实上，在4个月和8个月后，无论是经典的临床标准（里奇指数、李指数等）还是实验室标准（血沉）均未显示出任何具有统计学意义的变化。文中讨论了这些结果与先前发表的结果之间的差异。
