Husberg B, Ericsson H
Scand J Urol Nephrol Suppl. 1980;54:129-31.
A test system to evaluate the influence of antineoplastic drugs on the cell-mediated immune response evoked by an experimental rat carcinoma is presented. Thoracic Duct cells from W 49 tumor-bearing WF rats were added to monolayers of 51Cr-labelled tumor cells. A clear cytotoxic effect was noted. In vivo glucocorticoid treatment of rats after tumor inoculation prevented the appearance of such cells. In vivo tumor growth rate was not affected.
本文介绍了一种测试系统，用于评估抗肿瘤药物对实验性大鼠癌诱发的细胞介导免疫反应的影响。将来自携带W 49肿瘤的WF大鼠的胸导管细胞添加到51Cr标记的肿瘤细胞单层中。观察到明显的细胞毒性作用。肿瘤接种后对大鼠进行体内糖皮质激素治疗可阻止此类细胞的出现。体内肿瘤生长速率未受影响。
