Komalarini S, Njotosiswojo S, Rockhill R C, Lesmana M
Southeast Asian J Trop Med Public Health. 1980 Dec;11(4):539-42.
During an observation period of 20 months (from January 1978 to September 1979) 123 children with clinically suspected salmonellosis were admitted to the Department of Pediatrics, 70 males and 53 females varying in age from 17 days to 14 years. S. typhi or S. enteriditis was isolated from the stool, urine, blood or cerebrospinal fluid in 85% (105/123) of the cases. The results of the microbiologic examination showed that 28 out of the 105 cases (27%) were resistant to chloramphenicol of which the S. sero-group C1 was predominant. It appeared that 28 cases conformed to the clinical data. In all these cases chloramphenicol was replaced by other antibiotics according to the sensitivity test. The mortality rate was 7% (9/123). Four of the fetal cases were from the chloramphenicol resistant group.
在20个月的观察期内(从1978年1月至1979年9月),123名临床疑似沙门氏菌病的儿童被收治入儿科,其中70名男性,53名女性,年龄从17天至14岁不等。85%(105/123)的病例粪便、尿液、血液或脑脊液中分离出伤寒沙门氏菌或肠炎沙门氏菌。微生物学检查结果显示,105例病例中有28例(27%)对氯霉素耐药,其中C1血清群沙门氏菌占主导。似乎有28例符合临床数据。在所有这些病例中,根据药敏试验,氯霉素被其他抗生素替代。死亡率为7%(9/123)。其中4例死亡病例来自氯霉素耐药组。