Sneppen O, Heerfordt J, Dissing I, Jensen M, Møller J, Nørbjerg M
J Bone Joint Surg Am. 1978 Oct;60(7):966-9.
Fifty-four tumors or tumor-like conditions in bone were studied by numerically assessed 99m-technetium polyphosphate scintigraphy. The uptake was expressed as a ratio of the uptake in the tumor region to the uptake in a corresponding region in the contralateral part of the body. In the malignant tumors there was marked variation in the uptake within each individual tumor group, a variation that rendered a differential diagnosis impossible. In general, the uptake was fairly high in malignant tumors and lower in benign ones. A ratio below 1.5 suggested the likelihood that the lesion was benign. The ratios also varied considerably with the site of the tumor and the patients' ages. Relatively low ratios were found for tumors of the trunk and for juxta-articular tumors in children, whereas higher and more varied ratios were observed in tumors of the peripheral skeleton in adults. It is concluded that numerically assessed scintigraphy is not a useful supplement to other methods used for diagnosing bone tumors.
采用数字评估的锝-99m多聚磷酸盐闪烁扫描术对54例骨肿瘤或肿瘤样病变进行了研究。摄取情况以肿瘤区域摄取量与身体对侧相应区域摄取量的比值表示。在恶性肿瘤中，每个肿瘤组内的摄取情况存在显著差异，这种差异使得鉴别诊断无法进行。一般来说，恶性肿瘤的摄取量相当高，良性肿瘤的摄取量较低。比值低于1.5提示病变可能为良性。比值也因肿瘤部位和患者年龄的不同而有很大差异。躯干肿瘤和儿童关节周围肿瘤的比值相对较低，而成年人外周骨骼肿瘤的比值则较高且变化更大。得出的结论是，数字评估闪烁扫描术并非用于诊断骨肿瘤的其他方法的有用补充。
