de Rohan-Chabot P, Said G, Ziza J M
Ann Med Interne (Paris). 1980;131(8):483-8.
Idiopathic orthostatic hypotension (IOH) is a slowly progressive disease of the autonomic nervous system. The association of central lesions with those of IOH is characteristic of the Shy-Drager syndrome, which follows a rapidly unfavorable course, and can be distinguished from IOH, according to some authors, by anatomical and pharmacological features. Hemodynamic and pharmacological studies were conducted in 4 cases of IOH and 3 cases of the Shy-Drager syndrome in order to determine the localization and extent of the orthostatic regulatory disorder. No differences were found between the two groups and a common physiopathological mechanism for the two affections is suggested.
特发性直立性低血压（IOH）是一种自主神经系统的缓慢进展性疾病。中枢性病变与IOH病变相关是夏伊-德雷格综合征的特征，该综合征病情进展迅速且预后不良，据一些作者称，根据解剖学和药理学特征可将其与IOH区分开来。为了确定直立性调节障碍的定位和程度，对4例IOH患者和3例夏伊-德雷格综合征患者进行了血流动力学和药理学研究。两组之间未发现差异，提示这两种疾病存在共同的生理病理机制。
