Horii T, Ogawa T, Ogawa H
Cell. 1981 Mar;23(3):689-97. doi: 10.1016/0092-8674(81)90432-3.
Using a cloned fragment containing the lexA gene of E. coli, the entire nucleotide sequence of the lexA gene has been determined. The probable coding region of the lexA gene contains 606 nucleotide residues and encodes a single protein of 202 amino acids. The initiation site of in vitro transcription of the lexA messenger RNA has been determined by analysis of the 5' nucleotide sequence. Comparison of the DNA sequence of the promoter region of the lexA gene with that of the recA gene reveals the presence of sequences that are common to both. There is some similarity between the amino acid sequences of the lexA and the lambda repressor proteins.
利用包含大肠杆菌lexA基因的克隆片段，已确定lexA基因的完整核苷酸序列。lexA基因的可能编码区包含606个核苷酸残基，编码一种由202个氨基酸组成的单一蛋白质。通过对5'核苷酸序列的分析，已确定lexA信使核糖核酸的体外转录起始位点。将lexA基因启动子区域的DNA序列与recA基因的DNA序列进行比较，发现两者存在共同序列。lexA蛋白与λ阻遏蛋白的氨基酸序列之间存在一些相似性。
