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被排斥的人角膜移植片。II. 光镜和电镜研究。

Rejected human corneal grafts. II. Light and electron microscopic study.

作者信息

van der Want J J, Kok-van Alphen C C, Vrensen G, Völker-Dieben H J

出版信息

Doc Ophthalmol. 1981 Mar 20;50(2):343-56. doi: 10.1007/BF00158019.

DOI:10.1007/BF00158019
PMID:7014154
Abstract

Six rejected human corneal grafts out of a group of 40 'bad-risk corneas' were systematically studied by light and electron microscopy. Remarkable fine structural similarities in this sample of corneas were observed. Granulocytes, lymphocytes and plasma cells are common in all rejected grafts. Furthermore, the epithelial and endothelial linings and the stroma reveal the characteristic alterations. The observations indicate an immunological reaction of the recipient to the donor corneas.

摘要

在一组40个“高危角膜”中,对6个被排斥的人角膜移植片进行了光镜和电镜的系统研究。在这一样本的角膜中观察到了显著的精细结构相似性。粒细胞、淋巴细胞和浆细胞在所有被排斥的移植片中都很常见。此外,上皮和内皮衬里以及基质显示出特征性改变。这些观察结果表明受体对供体角膜产生了免疫反应。

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本文引用的文献

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A study of fixation for electron microscopy.电子显微镜固定研究。
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2
Corneal vascularization in experimental uveitis and graft rejection. An electron microscopic study.
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Histochemical localization of hydrolytic enzymes during corneal graft reaction.角膜移植反应期间水解酶的组织化学定位
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Lack of blood group antigen A on human corneal endothelium.
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8
Histocompatibility (HLA) antigens and keratoplasty.组织相容性(HLA)抗原与角膜移植术。
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9
[Experimentally induced immunological reaction of the eye after keratoplasty. II. Ultrastructural changes of the receptor's cornea (author's transl)].角膜移植术后眼部实验性诱导免疫反应。II. 受体角膜的超微结构变化(作者译)
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Feb 23;201(3):247-56. doi: 10.1007/BF02385182.
10
[Experimentally induced immonological reaction of the eye after keratoplasty. I. Lightmicroscopy (author's transl)].
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Feb 23;201(3):237-46. doi: 10.1007/BF02385181.