Phillips J I, Davies I
Invest Urol. 1981 May;18(8):422-5.
Histologic preparations of the urethras of 3 and 30-month-old virgin female C57 mice were stereologically analyzed with a light microscope with an eyepiece grid. Serial sections of entire urethras were stained and divided into ten representative regions; the component tissues of each region were analyzed. There was no significant change with age in the total muscle component in each region. The muscle, however, was divided into two types: muscle with and muscle without the infiltration of collagen fibers. The amount of muscle with collagen infiltration was significantly increased in some regions of the urethra in the 30-month-old group. There was no age-associated significant difference in the vascular or connective tissue components of the urethra. A difference in the glandular component was recorded in one region only, because of change in the ducts of the clitoral glands. We noted differences in the lumen and its epithelium that were attributable to the more open urethral lumen in the young group in certain regions.
使用带有目镜网格的光学显微镜对3个月和30个月大的未交配雌性C57小鼠的尿道组织切片进行体视学分析。对整个尿道的连续切片进行染色，并分为十个代表性区域；对每个区域的组成组织进行分析。每个区域的总肌肉成分随年龄没有显著变化。然而，肌肉分为两种类型：有胶原纤维浸润的肌肉和无胶原纤维浸润的肌肉。在30个月龄组的尿道某些区域，有胶原浸润的肌肉量显著增加。尿道的血管或结缔组织成分没有与年龄相关的显著差异。仅在一个区域记录到腺体成分的差异，这是由于阴蒂腺导管的变化。我们注意到管腔及其上皮存在差异，这归因于年轻组在某些区域尿道管腔更开放。
