• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Spectral alterations associated with the ligand-promoted gross conformational change in aspartate transcarbamoylase.

作者信息

Hu C Y, Howlett G J, Schachman H K

出版信息

J Biol Chem. 1981 May 25;256(10):4998-5004.

PMID:7014567
Abstract
摘要

相似文献

1
Spectral alterations associated with the ligand-promoted gross conformational change in aspartate transcarbamoylase.
J Biol Chem. 1981 May 25;256(10):4998-5004.
2
Calorimetric estimate of the enthalpy change for the substrate-promoted conformational transition of aspartate transcarbamoylase from Escherichia coli.大肠杆菌天冬氨酸转氨甲酰酶底物促进构象转变的焓变的量热法估计。
J Biol Chem. 1981 May 25;256(10):5005-15.
3
Revisiting the allosteric mechanism of aspartate transcarbamoylase.重新审视天冬氨酸转氨甲酰酶的变构机制。
Nat Struct Biol. 2002 Feb;9(2):87-9. doi: 10.1038/nsb0202-87.
4
Calorimetric analysis of aspartate transcarbamylase from Escherichia coli. Binding of substrates and substrate analogues to the native enzyme and catalytic subunit.
Biochemistry. 1978 Mar 7;17(5):784-90. doi: 10.1021/bi00598a005.
5
Ligand-promoted strengthening of interchain bonding domains in catalytic subunits of aspartate transcarbamoylase.
J Biol Chem. 1982 Oct 25;257(20):12214-8.
6
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation.双底物类似物的结合促进了天冬氨酸转氨甲酰酶非调节性催化三聚体的巨大结构变化：对别构调节的影响。
Proc Natl Acad Sci U S A. 2000 May 9;97(10):5077-82. doi: 10.1073/pnas.090087197.
7
Communication between polypeptide chains in aspartate transcarbamoylase. Conformational changes at the active sites of unliganded chains resulting from ligand binding to other chains.天冬氨酸转氨甲酰酶中多肽链之间的通讯。配体与其他链结合导致未结合配体的链的活性位点发生构象变化。
J Biol Chem. 1986 Mar 5;261(7):3079-84.
8
Phosphorus-containing inhibitors of aspartate transcarbamoylase from Escherichia coli.
FEBS Lett. 1990 Jan 29;260(2):206-8. doi: 10.1016/0014-5793(90)80104-q.
9
Bohr effect in Escherichia coli aspartate transcarbamylase. Linkages between substrate binding, proton binding, and conformational transitions.
Biochemistry. 1979 Jul 10;18(14):3008-15. doi: 10.1021/bi00581a016.
10
Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: effect of active-site ligands on the regulatory chains.镍（II）取代的天冬氨酸转氨甲酰酶构象变化的传播：活性位点配体对调节链的影响
Proc Natl Acad Sci U S A. 1980 Apr;77(4):1995-9. doi: 10.1073/pnas.77.4.1995.

引用本文的文献

1
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation.双底物类似物的结合促进了天冬氨酸转氨甲酰酶非调节性催化三聚体的巨大结构变化：对别构调节的影响。
Proc Natl Acad Sci U S A. 2000 May 9;97(10):5077-82. doi: 10.1073/pnas.090087197.
2
Assessment of the allosteric mechanism of aspartate transcarbamoylase based on the crystalline structure of the unregulated catalytic subunit.基于未调控催化亚基的晶体结构对天冬氨酸转氨甲酰酶变构机制的评估。
Proc Natl Acad Sci U S A. 1999 May 11;96(10):5388-93. doi: 10.1073/pnas.96.10.5388.