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小鼠流产与嗜肺巴斯德杆菌有关。

Abortion in mice associated with Pasteurella pneumotropica.

作者信息

Ward G E, Moffatt R, Olfert E

出版信息

J Clin Microbiol. 1978 Aug;8(2):177-80. doi: 10.1128/jcm.8.2.177-180.1978.

DOI:10.1128/jcm.8.2.177-180.1978
PMID:701461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC275183/
Abstract

Pasteurella pneumotropica was isolated from the uteri, fetuses, lungs, and spleens of aborting Swiss Carworth mice. Male mice in the colony carried P. pneumotropica in pharynges, testes, and seminal vesicles. Normal pregnant and nongravid females carried P. pneumotropica in the eye of 1 and in the uteri of 4 of 11. Pregnant mice from another colony did not abort when injected with P. pneumotropica. Necrotizing and suppurative metritis was found among aborting females with P. pneumotropica infections. Occurrence of malignant lymphoma and mammary adenocarcinoma among animals in this colony likely resulted in immunosuppression which could have predisposed animals to the diseases seen.

摘要

从流产的瑞士卡沃思小鼠的子宫、胎儿、肺和脾脏中分离出嗜肺巴斯德菌。该鼠群中的雄性小鼠在咽部、睾丸和精囊中携带嗜肺巴斯德菌。正常怀孕和未怀孕的雌性小鼠中，1只的眼部和11只中的4只的子宫中携带嗜肺巴斯德菌。来自另一个鼠群的怀孕小鼠注射嗜肺巴斯德菌后未发生流产。在感染嗜肺巴斯德菌的流产雌性小鼠中发现了坏死性和化脓性子宫炎。该鼠群中的动物发生恶性淋巴瘤和乳腺腺癌可能导致了免疫抑制，这可能使动物易患所观察到的疾病。

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Pasteurella pneumotropica evades the human complement system by acquisition of the complement regulators factor H and C4BP.嗜肺巴斯德菌通过获得补体调节因子H和C4结合蛋白来逃避人类补体系统。
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Isolation of Pasteurella ureae from reproductive tracts of congenic mice.从同源小鼠生殖道中分离出脲巴斯德氏菌。
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本文引用的文献

1
A pneumotropic pasteurella of laboratory animals; pathological and immunological studies with the organism.实验动物的嗜肺巴氏杆菌；对该微生物的病理学和免疫学研究
J Infect Dis. 1950 Mar-Apr;86(2):184-96. doi: 10.1093/infdis/86.2.184.
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A pneumotropic pasteurella of laboratory animals; bacteriological and serological characteristics of the organism.实验动物的嗜肺巴氏杆菌；该生物体的细菌学和血清学特征
J Infect Dis. 1950 Mar-Apr;86(2):172-83. doi: 10.1093/infdis/86.2.172.
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A study of latent Pasteurella infection in a mouse colony.一项关于小鼠群体中巴斯德氏菌潜伏感染的研究。
J Infect Dis. 1962 Sep-Oct;111:135-40. doi: 10.1093/infdis/111.2.135.
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Pasteurella meningitis.巴斯德菌性脑膜炎
Neurology. 1973 Oct;23(10):1097-100. doi: 10.1212/wnl.23.10.1097.
5
Experimental investigation of uterine infections of mice due to Pasteurella pneumotropica.嗜肺巴斯德杆菌引起小鼠子宫感染的实验研究
J Comp Pathol. 1972 Oct;82(4):471-5. doi: 10.1016/0021-9975(72)90047-3.
6
Variation in Pasteurella pneumotropica.嗜肺巴斯德氏菌的变异
J Med Microbiol. 1974 Feb;7(1):137-40. doi: 10.1099/00222615-7-1-137.
7
Uterine infections caused by bacteria and mycoplasma in mice and rats.
J Comp Pathol. 1972 Oct;82(4):477-82. doi: 10.1016/0021-9975(72)90048-5.
8
Septicaemia due to Pasteurella pneumotropica.嗜肺巴斯德杆菌所致败血症
J Clin Pathol. 1973 Jun;26(6):396-8. doi: 10.1136/jcp.26.6.396.
9
An eye infection in laboratory mice associated with Pasteurella pneumotropica.实验小鼠中与嗜肺巴斯德氏菌相关的眼部感染。
Lab Anim. 1975 Jul;9(3):197-200. doi: 10.1258/002367775780994556.

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