[血浆1,25-二羟维生素D的测定。成人的正常和病理值（作者译）]
[Measurement of plasma 1,25 dihydrovitamin D. Normal and pathological values in adults (author's transl)].
作者信息
Ulmann A, Lair M, Bader C, Funck-Brentano J L
出版信息
Nouv Presse Med. 1981 Apr 18;10(17):1393-5.
Plasma levels of 1,25 dihydrovitamin D (1,25 (OH)2D) were measured in normal subjects and in patients with various diseases, using a radiocompetition method. Mean values of 89 +/- 58 pmol/l (1 s.d.) were found in normal adults, irrespective of sex. Plasma 1,25 (OH)2D values were high in 12/31 patients with lithiasis and hypercalciuria, in 1/7 patients with lithiasis and normal calciuria and in 2/4 patients with idiopathic parathyroid adenoma; they were normal in 2 patients with essential hypoparathyroidism. 1,25(OH)2D was undetectable in 5 patients with chronic renal failure, low in 7 and normal in 4. Following successful kidney transplantation (serum creatinine less than 120 mumol/l) one-half of the patients had normal values and the other half high values.
采用放射竞争法测定了正常人和各类疾病患者血浆中1,25-二羟维生素D（1,25(OH)₂D）的水平。正常成年人无论性别，其平均水平为89±58 pmol/l（标准差为1）。在31例结石症和高钙尿症患者中有12例、7例结石症且钙尿正常的患者中有1例、4例特发性甲状旁腺腺瘤患者中有2例，其血浆1,25(OH)₂D值较高；2例特发性甲状旁腺功能减退患者的值正常。5例慢性肾衰竭患者检测不到1,25(OH)₂D，7例较低，4例正常。肾移植成功后（血清肌酐低于120 μmol/l），一半患者的值正常，另一半较高。
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