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通过吸附到合成免疫吸附剂上在体外和体内去除抗 A 红细胞抗体。

In vitro and in vivo removal of anti-A erythrocyte antibody by adsorption to a synthetic immunoadsorbent.

作者信息

Bensinger W I, Baker D A, Buckner C D, Clift R A, Thomas E D

出版信息

Transfusion. 1981 May-Jun;21(3):335-42. doi: 10.1046/j.1537-2995.1981.21381201809.x.

DOI:10.1046/j.1537-2995.1981.21381201809.x
PMID:7015594
Abstract

A solid-phase immunoadsorbent column using blood group A trisaccharide was tested in vitro and in vivo in dogs. This column was demonstrated to specifically remove anti-A antibody from human plasma in vitro and in vivo dogs specifically immunized with synthetic human blood group A trisaccharide. These studies indicate that this technique will be useful in removing anti-A and B antibody in marrow transplant recipients of incompatible marrow.

摘要

使用A血型三糖的固相免疫吸附柱在犬类身上进行了体外和体内测试。该柱在体外被证明能特异性地从人血浆中去除抗A抗体,在体内能从经合成人A血型三糖特异性免疫的犬类体内去除抗A抗体。这些研究表明,该技术将有助于在不相容骨髓的骨髓移植受者中去除抗A和抗B抗体。

相似文献

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In vitro and in vivo removal of anti-A erythrocyte antibody by adsorption to a synthetic immunoadsorbent.通过吸附到合成免疫吸附剂上在体外和体内去除抗 A 红细胞抗体。
Transfusion. 1981 May-Jun;21(3):335-42. doi: 10.1046/j.1537-2995.1981.21381201809.x.
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Immune adsorption of anti-A and anti-B antibodies.
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Transpl Int. 2005 Jan;17(11):666-72. doi: 10.1007/s00147-004-0775-7. Epub 2004 Nov 17.

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