Di Saia P J, Rich W M
Am J Obstet Gynecol. 1981 May 15;140(2):136-45. doi: 10.1016/0002-9378(81)90100-9.
Thirty-nine patients with multifocal carcinoma in situ of the vulva were managed with en bloc removal of the involved skin and a split-thickness skin graft to the surgical defect. The characteristic presentations of this clinical entity are reported and options for the therapy are discussed. Thirty-nine percent of the patients developed a recurrence, but none of the recurrences was within the donated skin graft. No reports of dyspareunia or seriously altered sexual function were noted. The details of the surgical approach ae outlined and modifications of the original procedure are described.
39例外阴多灶原位癌患者接受了整块切除受累皮肤并对手术缺损处进行中厚皮片移植的治疗。报告了该临床实体的特征性表现并讨论了治疗方案。39%的患者出现复发，但无一例复发发生在移植的皮肤处。未观察到性交困难或严重性功能改变的报告。概述了手术方法的细节并描述了对原始手术的改良。
