van Sickle W, Gerritsen G, Beuving L
Chronobiologia. 1981 Jan-Mar;8(1):1-9.
Twenty-four hour feeding patterns were determined for diabetic and normal Chinese hamsters. Plasma insulin, glucose and glucagon were determined for those time periods that corresponded to the high and low points of food intake and for 3 time periods during which the animals ate an intermediate quantity of food. There was no difference in the feeding pattern between groups though the diabetics consumed more food during a 24-h period. Plasma glucose, insulin and glucagon reached a peak during the nocturnal phase of feeding in the nondiabetic group. On the other hand, plasma glucose remained elevated over the entire time period in the diabetic group. Also, plasma insulin reached a peak during the daylight in the diabetics. There was no difference between groups in plasma glucagon.
测定了糖尿病和正常中国仓鼠的24小时进食模式。在与食物摄入量的高点和低点相对应的时间段，以及动物进食中等量食物的3个时间段，测定了血浆胰岛素、葡萄糖和胰高血糖素。尽管糖尿病组在24小时内消耗的食物更多，但两组之间的进食模式没有差异。在非糖尿病组中，血浆葡萄糖、胰岛素和胰高血糖素在夜间进食阶段达到峰值。另一方面，糖尿病组的血浆葡萄糖在整个时间段内都保持升高。此外，糖尿病组的血浆胰岛素在白天达到峰值。两组之间的血浆胰高血糖素没有差异。
