Kaplan R P, Touloukian J, Ahmed A R, Newcomer V D
J Am Acad Dermatol. 1981 Jun;4(6):682-7. doi: 10.1016/s0190-9622(81)70070-7.
A number of dermatologic conditions may have associated esophageal manifestations. Teleologically, this may be because both the skin and the esophagus are lined by stratified squamous epithelium. Bullous dermatoses that may produce blisters, erosions, and/or stricture of the esophagus include cicatricial pemphigoid, Hailey-Hailey disease, Darier's disease, various forms of epidermolysis bullosa, bullous pemphigoid, and pemphigus vulgaris. Very rarely, bullous diseases may affect the esophagus in such a manner that there is a sloughing of the entire mucous membrane. The production of such an esophageal cast has been termed esophagitis dissecans superficialis. This is the second case recorded in the medical literature of pemphigus vulgaris associated with esophagitis dissecans superficialis. Additionally, this is the first case of pemphigus vulgaris in which the esophagus is demonstrated to be positive by direct immunofluorescence.
许多皮肤病可能伴有食管表现。从目的论角度来看，这可能是因为皮肤和食管均由复层鳞状上皮覆盖。可能导致食管水疱、糜烂和/或狭窄的大疱性皮肤病包括瘢痕性类天疱疮、黑利-黑利病、达里埃病、各种类型的大疱性表皮松解症、大疱性类天疱疮和寻常型天疱疮。极罕见情况下，大疱性疾病可累及食管，导致整个黏膜脱落。这种食管管型的形成被称为浅表性剥脱性食管炎。这是医学文献中记录的第二例与浅表性剥脱性食管炎相关的寻常型天疱疮病例。此外，这是第一例经直接免疫荧光法证实食管呈阳性的寻常型天疱疮病例。
