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类固醇对伤口愈合的影响:文献综述

Effects of steroids on wound healing: a review of the literature.

作者信息

Goforth P, Gudas C J

出版信息

J Foot Surg. 1980 Spring;19(1):22-8.

PMID:7016965
Abstract

Since some podiatric surgeons are using glucocorticosteroids to minimize postoperative edema and pain associated with traumatic procedures, the effects on wound healing should be understood as much as possible so that maximum results can be achieved with minimal risk to the patient. Considerable animal and human research has been done on the potential wound-healing effects of glucocorticosteroids. Current studies indicate a detrimental wound-healing effect with the use of glucocorticosteroids. Increased infection will also be discussed.

摘要

由于一些足病外科医生正在使用糖皮质激素来尽量减少与创伤性手术相关的术后水肿和疼痛,因此应尽可能了解其对伤口愈合的影响,以便在对患者风险最小的情况下取得最大效果。关于糖皮质激素对伤口愈合的潜在影响,已经进行了大量的动物和人体研究。目前的研究表明,使用糖皮质激素会对伤口愈合产生有害影响。还将讨论感染增加的问题。

相似文献

1
Effects of steroids on wound healing: a review of the literature.类固醇对伤口愈合的影响:文献综述
J Foot Surg. 1980 Spring;19(1):22-8.
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The effects of different corticosteroids on the healing colon anastomosis and cecum in a rat model.不同皮质类固醇对大鼠模型中结肠吻合口和盲肠愈合的影响。
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Effects of corticosteroids on fibroblast functions.
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[Effect of glucocorticoids on the healing of clean wounds (review of the literature)].[糖皮质激素对清洁伤口愈合的影响(文献综述)]
Khirurgiia (Mosk). 1970 Oct;46(10):128-32.
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Steroid depressed wound healing and Tridax procumbens.
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[Study of action of certain steroids on chicken fibroblasts in culture in vitro].[某些类固醇对体外培养鸡成纤维细胞作用的研究]
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[Corticoids and wound granulation from experimental and clinical point of view].[从实验和临床角度看皮质类固醇与伤口肉芽形成]
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Glucocorticoid dynamics and impaired wound healing in diabetes mellitus.糖皮质激素动力学与糖尿病患者伤口愈合受损
Am J Pathol. 1998 Feb;152(2):547-54.
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Perioperative glucocorticoid coverage. A reassessment 42 years after emergence of a problem.围手术期糖皮质激素覆盖:问题出现42年后的重新评估
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[Modifying regeneration success of glued nerve anastomosis by local corticoid administration].[通过局部给予皮质类固醇改善粘合神经吻合术的再生成功率]
Unfallchirurgie. 1990 Jun;16(3):144-50. doi: 10.1007/BF02588011.