Lee Y T, Hori J M
J Surg Oncol. 1981;17(2):189-93. doi: 10.1002/jso.2930170215.
This is a retrospective study of 163 patients with Hodgkin disease and 364 patients with other lymphomas who were admitted to one Cancer Hospital (1940--1971). All the histological slides were reviewed and reclassified by one pathologist. In patients who had multiple and sequential biopsies (16 with Hodgkin disease and 97 with non-Hodgkin lymphomas), the histological subtypes remained the same in over 60% of the cases. When changes did occur, the neoplasms progressed toward histologically more malignant forms.
这是一项对163例霍奇金病患者和364例其他淋巴瘤患者的回顾性研究，这些患者均于一家癌症医院住院（1940 - 1971年）。所有组织学切片均由一名病理学家重新审查和分类。在进行了多次连续活检的患者中（16例霍奇金病患者和97例非霍奇金淋巴瘤患者），超过60%的病例组织学亚型保持不变。当确实发生变化时，肿瘤会向组织学上更恶性的形式发展。
